abstract：BACKGROUND:Non-heart-beating donors suffer a period of warm ischaemia (WI) injury, resulting in higher rates of delayed graft function compared with heart-beating donors. Endothelin is believed to play a pathophysiological role in the intense vasospasm associated with WI. This study aimed to investigate renal function ...

journal_title：Journal of nephrology

authors： Mann CD,Metcalfe MS,Nicholson ML

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:This study is part of a 3-country study testing whether normal levels of hemoglobin (Hgb) delay the progression of left ventricular (LV) growth in chronic kidney disease (CKD) patients not on dialysis. METHODS:This was an open-label, randomized, multicenter, controlled trial conducted in 27 tertiary-care ho...

journal_title：Journal of nephrology

authors： Cianciaruso B,Ravani P,Barrett BJ,Levin A,ITA-EPO-7 investigators.

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:The G-1082A polymorphism of the interleukin-10 (IL-10) gene has been associated with modified gene expression and the progression of primary IgA nephropathy (IgAN). In the present study, we evaluated its influence on recurrent IgAN after renal transplantation. METHODS:We studied 103 patients who suffered fr...

journal_title：Journal of nephrology

authors： Bantis C,Heering PJ,Aker S,Schwandt C,Grabensee B,Ivens K

更新日期：2008-11-01 00:00:00

abstract：:The pathophysiological mechanisms underlying preeclampsia, a serious complication of pregnancy, are largely unknown. Since, on the other hand, the various risk factors are known, primary and secondary prevention with pre- and inter-pregnancy counseling should be undertaken, and a follow-up should be conducted to evalu...

journal_title：Journal of nephrology

authors： Buemi M,Bolignano D,Barilla A,Nostro L,Crasci E,Campo S,Coppolino G,D'Anna R

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Adiponectin, a novel adipocytokine with antiinflammatory and antiatherosclerosis properties, has been found to be an inverse predictor of cardiovascular outcomes among uremic patients on hemodialysis. However, its role in uremic patients on continuous ambulatory peritoneal dialysis (CAPD) remains unclear. Th...

journal_title：Journal of nephrology

authors： Tsao YT,Hsu YJ,Chu NF,Lai CH,Chiu JS,Lin SH

更新日期：2008-09-01 00:00:00

abstract：:Bisphosphonates inhibit bone resorption and are widely used to treat osteolytic metastases and osteoporosis. Renal osteodystrophy patients have continuous bone loss due to chronically elevated parathyroid hormone (PTH). In this open-label study, ibandronate was evaluated for the treatment of reduced bone density in re...

journal_title：Journal of nephrology

authors： Bergner R,Henrich D,Hoffmann M,Schmidt-Gayk H,Lenz T,Upperkamp M

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Early initiation of therapy is warranted for patients with idiopathic membranous nephropathy (IMN) who have severe proteinuria. Therapy with tacrolimus (TAC) or intravenous cyclophosphamide (CYC) may be an option in treating such patients. METHODS:This prospective cohort study included patients with IMN who...

journal_title：Journal of nephrology

authors： Li X,Lv R,He Q,Li H,Du X,Lin W,Li Q,He X,Wang S,Chen J

更新日期：2008-07-01 00:00:00

abstract：:Nephrogenic systemic fibrosis (NSF) / nephrogenic fibrosing dermopathy (NFD) is a recently described disease, occurring only in patients with variable degrees of renal failure (RF) previously exposed to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging. Public advisories are consistent on some ke...

journal_title：Journal of nephrology

authors： Canavese C,Mereu MC,Aime S,Lazzarich E,Fenoglio R,Quaglia M,Stratta P

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The effect of uric acid on nocturnal dipping in hypertensive patients is unknown. We analyzed the specific relationship between uric acid and nocturnal dipping status in newly diagnosed essential hypertensive patients with normal renal function. METHODS:Two hundred fifteen patients with newly diagnosed esse...

journal_title：Journal of nephrology

authors： Afsar B,Elsurer R,Ozdemir FN,Sezer S

更新日期：2008-05-01 00:00:00

abstract：:This review summarizes the plausible mechanisms of carcinogenesis, critically analyzes the literature on cancer risk and discusses issues of cancer screening in chronic dialysis patients. Despite conflicting results among various studies, there is sufficient evidence to conclude that there is a heightened incidence of...

journal_title：Journal of nephrology

authors： Mandayam S,Shahinian VB

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is an important risk factor for all-cause mortality. In the general population, physical activity is associated with reduced mortality. We examined the association of level of physical activity with mortality in patients with predominantly nondiabetic CKD stage 3-4. METHODS:We s...

journal_title：Journal of nephrology

authors： Chen JL,Lerner D,Ruthazer R,Castaneda-Sceppa C,Levey AS

更新日期：2008-03-01 00:00:00

abstract：:Renal transplantation is associated with better survival and improved quality of life compared to maintenance dialysis. Although many sleep disorders improve or even disappear after a successful transplantation, sleep quality remains low, and the prevalence of sleep complaints, although lower than in dialysis patients...

journal_title：Journal of nephrology

authors： Sabbatini M,Pisani A,Crispo A,Nappi R,Gallo R,Cianciaruso B,Federico S

更新日期：2008-03-01 00:00:00

abstract：:The goal of palliative care is to achieve good quality of life for patients with chronic life-limiting illnesses, and their families, through assessment and management of physical, psychosocial and spiritual problems and needs. Patients with kidney diseases present a particular target of such care from the time of dia...

journal_title：Journal of nephrology

authors： Lichodziejewska-Niemierko M,Rutkowski B

更新日期：2008-03-01 00:00:00

abstract：:Autosomal recessive and autosomal dominant polycystic kidney disease (ADPKD and ARPKD) are 2 major variants of inherited diseases leading to the cystic degeneration of the kidney and other organs. Primary cilia have moved into the focus of research as it is becoming increasingly clear that dysfunction of this special ...

journal_title：Journal of nephrology

authors： Wagner CA

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Several studies have suggested an effect of calcineurin inhibitors on arterial compliance in kidney transplant recipients. We aimed to investigate whether the type of calcineurin inhibitor influences large and small artery compliance in these patients independently of other determinants. METHODS:Patients ...

journal_title：Journal of nephrology

authors： Wystrychowski G,Chudek J,Zukowska-Szczechowska E,Wiecek A,Grzeszczak W

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Because urinary low molecular weight protein (LMWP) measurement shows changes in renal integrity at an early stage, beta2-microglobulin (B2m), retinol-binding protein (RBP) and alpha1-microglobulin (A1m) were evaluated in 24-hour urine collection of 65 patients with pure monoclonal light chain (MLC) proteinu...

journal_title：Journal of nephrology

authors： Madalena L,Facio ML,Angerosa M,Pandolfo M,Bresciani P,Alejandre M,Pizzolato M,Toblli JE

更新日期：2007-11-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of the poor long-term survival of patients with chronic kidney disease (CKD). Anemia, which is a frequent and early complication of CKD, not only impairs patients' quality of life, but also is an independent risk factor for adverse cardiovascular outcomes. This may be due to...

journal_title：Journal of nephrology

authors： Locatelli F,Del Vecchio L,Pozzoni P

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The endogenous inhibitor of nitric oxide synthase (NOS), asymmetric dimethylarginine (ADMA), is implicated in endothelial dysfunction and is a marker of renal disease progression and cardiovascular (CV) complications. Various cell species exhibit the enzymatic system that generates and degrades this methylar...

journal_title：Journal of nephrology

authors： Spoto B,Parlongo RM,Parlongo G,Sgro' E,Zoccali C

更新日期：2007-09-01 00:00:00

abstract：:Glomerulonephritis rarely appears associated with Hodgkin's disease or non-Hodgkin's lymphoma (NHL). We present a patient with a relapse of a non-Hodgkin's lymphoma which first presented as nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS). This case report discusses the unusual association of non-Ho...

journal_title：Journal of nephrology

authors： González García E,Olea T,Hevia C,Torre A,Azorin S,Ruiz E,Martínez Ara J,Sánchez Villanueva R,Fernandez EJ,Selgas R

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:A sensitive, feasible and reproducible marker for renal function is necessary to evaluate the clinical efficacy of enzyme replacement therapy (ERT) in Fabry nephropathy. Serum creatinine has some limitations and cystatin C has been proposed, in other nephropathies, as a useful marker of renal function. The u...

journal_title：Journal of nephrology

authors： Feriozzi S,Germain DP,Di Vito R,Legrand A,Ricci R,Barbey F

更新日期：2007-07-01 00:00:00

abstract：:Membranous nephropathy (MN) is a glomerular disease characterized by proteinuria, usually in a nephrotic range, and variable natural course. The etiology is unknown in many cases, while in some patients, MN may be secondary to infection, to other diseases, or to exposure to drugs and toxic substances. In idiopathic MN...

journal_title：Journal of nephrology

authors： Ponticelli C

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:An increased number of major histocompatibility complex (MHC) class II-positive cells (OX-6+ cells) were observed in the glomerulus and periglomerular interstitium during the course of anti-glomerular basement membrane (anti-GBM) crescentic glomerulonephritis (GN) in WKY rats. This study aimed to demonstrate...

journal_title：Journal of nephrology

authors： Fujinaka H,Nameta M,Kovalenko P,Matsuki A,Kato N,Nishimoto G,Yoshida Y,Yaoita E,Naito M,Kihara I,Tomizawa S,Yamamoto T

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIMS:It has been well documented that gene and DNA alterations occur frequently in benign primary parathyroid adenomas as well as in parathyroid glands with secondary hyperplasia. However, it has not been shown whether a correlation exists between somatic DNA aberrations and clinical data. METHODS:We an...

journal_title：Journal of nephrology

authors： Chudek J,Nagy A,Kokot F,Podwinski A,Wiecek A,Ritz E,Kovacs G

更新日期：2007-03-01 00:00:00

abstract：:A 17-year-old boy was admitted to the hospital twice in a year for 2 episodes of hemolytic uremic syndrome (HUS). During these 2 HUS episodes he had diarrhea, decreased serum complement, decreased total protein and decreased serum albumin concentrations. We suggest that protein-losing enteropathy and hypocomplementemi...

journal_title：Journal of nephrology

authors： Kalman S,Bakkaloğlu S,Dalgiç B,Ozkaya O,Söylemezoğlu O,Buyan N

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The response of proximal convoluted tubules (PCTs) to angiotensin II is mediated by specific type 1 receptors found on both apical and basolateral surface membrane cells. After ligand association with type 1 receptors, different signaling pathways are triggered and determine changes in fluid absorption (Jv)....

journal_title：Journal of nephrology

authors： Bertels IM,Gontijo JA,Figueiredo JF

更新日期：2007-01-01 00:00:00

abstract：:Minoxidil is frequently used in patients with advanced renal disease who have been unresponsive to other antihypertensive agents. We describe a case of a 50-year-old man with chronic renal failure who was hospitalized complaining of a 2-week history of sore throat that had progressed to severe oral lesions and multipl...

journal_title：Journal of nephrology

authors： Callen EC,Church CO,Hernandez CL,Thompson ED

更新日期：2007-01-01 00:00:00

abstract：:There have been dramatic increases in the understanding of the molecular mechanisms involved in membranous nephropathy (MN) over the past 2 decades. Most of these have come directly from studies carried out in the Heymann nephritis models of MN in rats, which closely simulate the clinical and pathologic features of th...

journal_title：Journal of nephrology

authors： Couser WG,Nangaku M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease is a risk factor for death in the year following myocardial infarction or coronary angioplasty. Whether the risk is similar after coronary stenting, whether impaired renal function is associated with an increased risk of cardiovascular death or myocardial infarction (MI) after coronary...

journal_title：Journal of nephrology

authors： Charytan DM,Kuntz RE,Chhabra A,Cutlip DE

更新日期：2006-11-01 00:00:00

abstract：:Wilson's disease is an autosomal recessive disorder of hepatobiliary copper metabolism. Glomerular diseases can ensue during the course of Wilson's disease and membranous nephropathy is the eventual pathology in the majority of these cases. Membranoproliferative glomerulonephritis (MPGN) has rarely been reported in pa...

journal_title：Journal of nephrology

authors： Ozçakar ZB,Ekim M,Ensari A,Kuloglu Z,Yüksel S,Acar B,Kirsaçlioglu C,Kansu A,Yalçinkaya F,Girgin N

更新日期：2006-11-01 00:00:00

abstract：:Icodextrin, a glucose polymer, is widely used as an alternative to glucose as the osmotic agent in peritoneal dialysis (PD). We describe a case of a continuous ambulatory peritoneal dialysis patient who developed severe cutaneous hypersensitivity after initiation of icodextrin PD solution. Erythematous skin lesions gr...

journal_title：Journal of nephrology

authors： Lee SH,Park HC,Sim SR,Chung SJ,Kim KJ,Park WI,Hong SW,Ha SK

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:In end-stage renal disease (ESRD) patients on hemodialysis (HD) there may be a link between oxidative stress, genomic damage and the tendency of peripheral lymphocytes to die by apoptosis. Our aim was to verify this hypothesis, and to ascertain whether the link, if present, could explain lymphopenia in uremi...

journal_title：Journal of nephrology

authors： Pernice F,Floccari F,Nostro L,Caccamo C,Belghity N,Mantuano S,Romeo A,Barilla' A,Aloisi C,Ruello A,Frisina N,Buemi M

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Renal tubular epithelial cells (TECs) function as antigen-presenting cells because they constitutively express MHC class II molecules and have the ability to present peptide antigen to CD4+T cells. However, the costimulatory signals provided by TECs for optimal T-cell activation have not been fully character...

journal_title：Journal of nephrology

authors： Zhang J,Chen Y,Li J,Zhang R,Wu Y,Zou L,Zhao T,Zhang X,Han J,Chen A,Wu Y

更新日期：2006-07-01 00:00:00

abstract：:Colchicine is an effective antiinflammatory medication. It should be used with great caution, however, in patients requiring dialysis. Coadministration of colchicine and macrolides may impair colchicine elimination, resulting in excess drug exposure and toxicity. We report 2 renal failure cases of colchicine intoxicat...

journal_title：Journal of nephrology

authors： Akdag I,Ersoy A,Kahvecioglu S,Gullulu M,Dilek K

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Removal of anti-glomerular basement membrane (anti-GBM) antibody by extracorporeal treatment including plasmapheresis or immunoadsorption (IA) has been considered an effective method in the treatment of Goodpasture's syndrome. In this study, we investigated the effect of IA on serum anti-GBM level and evalua...

journal_title：Journal of nephrology

authors： Hu W,Liu Z,Ji D,Xie H,Gong D,Li L

更新日期：2006-05-01 00:00:00

abstract：:Renal involvement is uncommon in the rare condition of Type I cryoglobulinaemia. On review of the literature most cases featured membranoproliferative glomerulonephritis on renal biopsy. In this case report, we describe a presentation of rapidly progressive glomerulonephritis that histologically demonstrated necrotisi...

journal_title：Journal of nephrology

authors： Boudville N,Walton J,House AA

更新日期：2006-05-01 00:00:00

abstract：:The origin of the Teutonic Order of Hospitalers St. Mary (Ordo Hospitalis S. Mariae Teutonicorum Hi-erosolymitani) is presented. The St. Mary Hospitaler Teutonic Order arrived in the XIIIth century to Pomezania, then inhabited by pagan Prussian tribes. The Knights of the Order started to Christianize the Prussians, th...

journal_title：Journal of nephrology

authors： Zydowo MM

更新日期：2006-05-01 00:00:00

abstract：:John Allen, a British physician of the eighteenth century, deserves being remembered for a series of inventions, but most importantly -- from a 'medical' point of view -- for his highly praised manuscript, the 'Universae Medicinae Practicae,sive Doctissimorum Virorum de Morbis Eorumque Causis ac Remediis Judicia', whi...

journal_title：Journal of nephrology

authors： Mezzogiorno A,Iorio L,Esposito A,Flamourakis M,Esposito V

更新日期：2006-05-01 00:00:00

abstract：:Modern nephrology developed in Poland mostly from the internal medicine department chaired in Warsaw by the great internist prof. Witold Orłowski (1874-1966). Three of his pupils Tadeusz Orłowski, Jan Roguski and Jakub Penson independently established the foundations of clinical nephrology and renal replacement therap...

journal_title：Journal of nephrology

authors： Czekalski S,Rutkowski B

更新日期：2006-05-01 00:00:00

abstract：QUESTIONS:- To what extent can ailing kidneys adapt their functions to the demands of pregnancy? - What risks is the nephropathic patient prone to throughout pregnancy compared with those of the general population, and which specific risks does her kidney disease determine? - What risks is the baby of a nephropathic pr...

journal_title：Journal of nephrology

authors： Stratta P,Canavese C,Quaglia M

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Accurate assessment of kidney function level is the key to the identification and management of chronic kidney disease (CKD). Glomerular filtration rate (GFR) is the best measure of overall kidney function in health and disease. There is no consensus about the method to be used routinely to measure and/or es...

journal_title：Journal of nephrology

authors： Nóbrega AM,Gomes CP,Lemos CC,Bregman R

更新日期：2006-03-01 00:00:00